Genetic basis of pediatric epilepsy syndromes
نویسندگان
چکیده
منابع مشابه
Genetic basis of pediatric epilepsy syndromes
Childhood epilepsy affects ~0.5-1% in the general population worldwide. Early-onset epileptic encephalopathies are considered to be severe neurological disorders, which lead to impaired motor, cognitive, and sensory development due to recurrence of seizures. Many of the observed epilepsy phenotypes are associated with specific chromosomal imbalances and thus display gene dosage effects, and als...
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OBJECTIVES Epidemiologic data concerning idiopathic generalized epilepsies (IGEs) are scarce or often unreliable. In the current study, we specifically analyzed the syndromes of IGE based on their demographic, clinical, and EEG findings to determine if other than the seizure type(s) and age of onset, there are any other distinctive features to distinguish these syndromes of IGEs from one anothe...
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Genetic generalized epilepsy (GGE) consists of several syndromes diagnosed and classified on the basis of clinical features and electroencephalographic (EEG) abnormalities. The main EEG feature of GGE is bilateral, synchronous, symmetric, and generalized spike-wave complex. Other classic EEG abnormalities are polyspikes, epileptiform K-complexes and sleep spindles, polyspike-wave discharges, oc...
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This is a quick reference for epilepsy syndromes that are listed by the International League Against Epilepsy (ILAE). Most of the syndromes are described in detail in the ILAE website: http://www.ilae-epilepsy.org/ctf/syn_frame.html. The following features are outlined for each epilepsy syndrome: seizure types; ictal EEG and interictal EEG features; activating effects of sleep, sleep deprivatio...
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ژورنال
عنوان ژورنال: Experimental and Therapeutic Medicine
سال: 2017
ISSN: 1792-0981,1792-1015
DOI: 10.3892/etm.2017.4267